Ponatinib is a kinase inhibitor indicated for the treatment of adult patients with chronic phase, accelerated phase, or blast phase chronic myeloid leukemia (CML) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy or Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy. This indication is based upon response rate. There are no trials verifying an improvement in disease-related symptoms or increased survival with Iclusig.
Ponatinib was approved by the US FDA on December 14, 2012, for patients with resistant or intolerant CML and Ph+ ALL, based on results of the PACE phase II trial reported days earlier at the annual ASH meeting. Because the approval was under the FDA Accelerated Approval program the applicant was required to carry out additional studies. Based on these additional studies, the FDA granted in 2016 full approval and updated the label to include patients with chronic phase, accelerated phase, or blast phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia for whom no other tyrosine kinase inhibitor therapy is indicated. Approval was also granted for T315I-positive and T315I-positive Philadelphia chromosome positive acute lymphoblastic leukemia.
Source Content From US FDA
Brand Name "Ponatinib tablets" medication can be imported and made available on "Named Patient Program (NPP)" treatment in Philippines, Vietnam, Ireland and India. Please contact at +91 9910645395 (Mr. Rakesh) or make an enquiry at info@cancermedicinesnetwork to find the cost price to buy "Ponatinib tablets" online and have it delivered where you live. We take guarantee of quality and delivery as per the buyer’s requirements.
Dear Rakesh and Colleagues,
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Patient, Physcian, distributor/supplier can buy and import Brand Name "Ponatinib tablets" from Verve Biosciences, if the drug has not been approved or is not available in your country. Make an enquiry and we will help you calculate the total price to buy "Ponatinib tablets" online and have it delivered where you live. From your side, we’ll simply need a prescription from your treating doctor. In some countries we might also need an import license. Our Patient Support team will guide you throughout the process.
Verve Biosciences facilitates import of anti-cancer medicines Ponatinib tablets, Make an enquiry to find the total cost of Ponatinib tablets in UAE, Iraq, Iran, Saudi Arabia, Jordan, Mexico, Argentina, Brazil, Chile, Colombia, Peru, Venezuela. Europe – Romania, Switzerland, Georgia, Turkey, Italy, UK, Ukraine, Azerbaijan, Latvia, Poland, Slovakia. Russia CIS – Armenia, Kazakhstan, Moldova, Tajikistan, Turkmenistan, Uzbekistan, Mongolia, Algeria, Mauritius, Uganda, Zimbabwe. Australia and New Zealand.